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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMP11
All Species:
20
Human Site:
T279
Identified Species:
48.89
UniProt:
P24347
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P24347
NP_005931.2
488
54618
T279
G
P
Q
A
G
I
D
T
N
E
I
A
P
L
E
Chimpanzee
Pan troglodytes
XP_515022
469
52600
T260
G
P
Q
A
G
I
D
T
N
E
I
A
P
L
E
Rhesus Macaque
Macaca mulatta
XP_001083910
488
54748
T279
G
P
Q
A
G
I
D
T
N
E
I
A
P
L
E
Dog
Lupus familis
XP_543534
489
54823
T280
G
P
Q
A
G
V
D
T
N
E
I
A
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q02853
492
55423
T283
S
S
Q
A
G
T
D
T
N
E
I
A
L
L
E
Rat
Rattus norvegicus
Q499S5
491
55493
T282
S
S
Q
A
G
T
D
T
N
E
I
A
L
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232777
502
56708
L291
A
E
L
P
Q
P
D
L
E
T
N
E
I
T
N
Frog
Xenopus laevis
Q11005
477
54423
E267
E
V
N
Q
V
E
N
E
S
N
E
I
P
A
A
Zebra Danio
Brachydanio rerio
XP_692205
483
55535
P288
N
D
I
P
S
A
F
P
P
D
A
C
H
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780356
489
56331
R261
G
D
R
F
I
P
L
R
P
Q
P
S
P
P
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93
97.3
86.9
N.A.
81.7
81.6
N.A.
N.A.
64.3
61.4
56.3
N.A.
N.A.
N.A.
N.A.
39.8
Protein Similarity:
100
93.4
97.7
91.4
N.A.
87.4
86.7
N.A.
N.A.
73.9
73.9
67.4
N.A.
N.A.
N.A.
N.A.
53.1
P-Site Identity:
100
100
100
93.3
N.A.
73.3
66.6
N.A.
N.A.
6.6
6.6
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
73.3
66.6
N.A.
N.A.
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
60
0
10
0
0
0
0
10
60
0
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
20
0
0
0
0
70
0
0
10
0
0
0
0
20
% D
% Glu:
10
10
0
0
0
10
0
10
10
60
10
10
0
0
60
% E
% Phe:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
10
30
0
0
0
0
60
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
10
10
0
0
0
0
20
50
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
10
0
60
10
10
0
0
0
10
% N
% Pro:
0
40
0
20
0
20
0
10
20
0
10
0
60
10
0
% P
% Gln:
0
0
60
10
10
0
0
0
0
10
0
0
0
10
0
% Q
% Arg:
0
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
20
20
0
0
10
0
0
0
10
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
20
0
60
0
10
0
0
0
20
0
% T
% Val:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _